Funded Initiatives

Functional & Restorative

In Vivo, Hypothalamic Deep Brain Stimulation (DBS) for Weight Loss in Rat Obesity Model.

Evaluating the feasibility and effectiveness of chronic deep brain stimulation of the feeding center, ventromedial hypothalamus (VHM) of obese rats to effect weight loss. 2003 NeuroGrant Recipient

Deep Brain Stimulation for Treatment of Obesity: Chronic Stimulatory Inhibition of the Lateral Hypothalamic Area and Effects on Food Intake and Weight in the Rat

Evaluating the feasibility and effectiveness of chronic deep brain stimulation to the lateral hypothalamus of obese rats to effect weight loss.

A Direct Brain-to-Speech Generator for Use in Humans

Investigating the possibility of direct brain-to-speech activity in locked-in patients. 2004 NeuroGrant Recipient

Chronic Bilateral Deep Brain Stimulatory Inhibition of the Lateral Hypothalamus for Treatment of Obesity in the Primate

To determine if bilateral deep brain stimulation of the Lateral Hypothalamus will lead to significant and sustained weight loss in primates. 2004 NeuroGrant Recipient

Trigeminal Neuralgia Patient and Provider Education Program

Training program for providers and the community to increase awareness and improve treatment for patients suffering from trigeminal neuralgia. 2005 NeuroGrant Recipient

Impact of Deep Brain Stimulation in the Sub-Thalamic Nucleus of Patients with Parkinson’s Disease on Behavior and Mood

Prospective longitudinal study to assess the impact of deep brain stimulation on behavior and mood in patients with idiopathic Parkinson’s Disease. 2005 NeuroGrant Recipient

Safety and Efficacy of Deep Brain Stimulation (DBS) of the Globus Pallidus Internus (Gpi) in Dystonia

Assessing the safety and efficacy of bilateral deep brain stimulation of the Globus Pallidus Internus in medically refractory dystonia. 2003 NeuroGrant Recipient

Quality of Life Outcomes and Caregiver Burden in Patients with Advanced Parkinson’s Disease Treated with Unilateral Deep Brain Stimulation of the Sub-Thalamic Nucleus

To determine the impact of unilateral deep brain stimulation of the Sub-Thalamic Nucleus (STN) on self reported quality of life measures and perceived caregiver burden in patients with advanced Parkinson’s disease and their families. 2004 NeuroGrant Recipient

Host Immunological Response to Transplantation of Stem Cells

Evaluating the immunological potential for the rejection of stem cell grafts in the treatment of MPTP-induced Parkinson-like symptoms. 2005 NeuroGrant Recipient

Microelectrode Signal Analysis

Elucidating the pathophysiology of patients with unusual diseases undergoing deep brain stimulation through the analysis of firing patterns. 2005 NeuroGrant Recipient

Transplantation of Human Stem Cells of Hematopoietic Origin into a 6-Hydroxydopamine Rodent Model of Parkinson's Disease: To Repair, Replace, or Regenerate Dopaminergic Tissue in the Nigral-Striatal Pathway.

To determine the viability and potential for human hematopoietic stem cells either in their heterogeneous form or directed toward a DA phenotype, to repair, replace, or regenerate the loss of DA in the striatum in rats pre-treated with a DA neurotoxin. 2007 NeuroGrant Recipient

Adult Hippocampal Neurogenesis in Mouse Models of Familial Alzheimer's Disease

To elucidate the molecular mechanisms underlying the effect at early onset Familial Alzheimer's Disease (FAD)-linked Presenilin 1 on adult neurogenesis. 2008 NeuroGrant Recipient

Back To Top ↑

Areas of focus


Type of project

“The CINN Associates strive to assist CINN in improving the lives of individuals with neurologic disorders such as stroke, brain tumors, epilepsy, Parkinson's disease, spinal cord injury and other back problems.”

For more information on how to become a CINN Associate or to speak with an Associate, please contact The CINN Foundation at 773/250.0300 or